What is HOMERuN?

The Hospital Medicine Reengineering Network (HOMERuN) was established in 2011 to advance the field of Hospital Medicine by supporting and conducting rigorous, multi-center research studies to improve the care of patients with acute illnesses.

HOMERuN began as a collaboration among Hospitalists and researchers at 13 academic medical centers, with a focus on improving transitions of care, but has since expanded its reach to include our most important stakeholder — The Patient. We have an active Patient and Family Advisory Council, which meets regularly to share valuable experiences and feedback for quality improvements in the program.

Among a large portfolio of funded research, HOMERuN has supported multiple studies focusing on avoidable and preventable readmissions, understanding the impact of lab testing on patient management, and working with an established collaborative research group to expand their inpatient-focused data model.


HOMERuN was recently awarded an AHRQ grant to fund one of the largest studies examining the frequency of diagnostic errors in US hospitals. The UPSIDE (Utility of Predictive Systems in Diagnostic Errors) study is taking a direct look at one of the primary quality of care challenges, diagnostic errors, to help understand their impact on patient outcomes and how to avoid them in the future.


As of early 2020, we have initiated a response to gather and share information, and identify needs that are critical during the COVID-19 outbreak.

HOMERuN's Core Values

Every patient receives care which is safe, effective, and in accordance with their values and wishes.

Research is informed by the voices of patients, providers, and health care systems.

Innovations and learning are intended for application across the health care continuum.

We ensure that our research and innovations actually help patients.

We provide inspiration and mentorship for the next generation of Hospital Medicine researchers.