What is HOMERuN?

The Hospital Medicine Reengineering Network (HOMERuN) was established in 2011 to advance the field of Hospital Medicine by supporting and conducting rigorous, multi-center research studies to improve the care of patients with acute illnesses.

HOMERuN began as a collaboration among Hospitalists and researchers at 13 academic medical centers, with a focus on improving transitions of care, but has since expanded its reach to include our most important stakeholder — The Patient. We have an active Patient and Family Advisory Council, which meets regularly to share valuable experiences and feedback for quality improvements in the program.

Among a large portfolio of funded research, HOMERuN has supported multiple studies focusing on avoidable and preventable readmissions, understanding the impact of lab testing on patient management, and working with an established collaborative research group to expand their inpatient-focused data model.


To transform care of patients with acute illness through the discovery and implementation of innovations in health care.


Ensure that every hospitalized patient receives the best quality, safest, and highest value care from hospitalization through recovery.

HOMERuN fulfills its mission by focusing on the following key goals:

  1. To build evidence base in Hospital Medicine through conduct of studies that answer questions important for patient care, hospitalists’ practice, and/or policy.
  2. Implement our research via collaborative, multi-site, interdisciplinary, rigorously-designed and conducted studies that emphasize translating evidence-based improvements into practice.
  3. Promote research capacity in the field of Hospital Medicine through cultivating skills, resources, and expertise at the levels of investigator, organization and national healthcare system.
  4. In collaboration with key stakeholders, to broadly disseminate results of Hospital Medicine research so as to effect change in clinical practice and healthcare policy.


HOMERuN was recently awarded an AHRQ grant to fund one of the largest studies examining the frequency of diagnostic errors in US hospitals. The UPSIDE (Utility of Predictive Systems in Diagnostic Errors) study is taking a direct look at one of the primary quality of care challenges, diagnostic errors, to help understand their impact on patient outcomes and how to avoid them in the future.

HOMERuN's Core Values

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Every patient receives care which is safe, effective, and in accordance with their values and wishes.

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Research is informed by the voices of patients, providers, and health care systems.

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Innovations and learning are intended for application across the health care continuum.

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We ensure that our research and innovations actually help patients.

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Improvements in care remove structures of racism and oppression in medicine and society.

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We provide inspiration and mentorship for the next generation of Hospital Medicine researchers.