HOMERuN Current Projects


RELIANCE is a multi-site, nationwide clinical research project funded by the Patient-Centered Outcomes Research Institute (PCORI) to compare the real-world effectiveness of long-term oral roflumilast vs. azithromycin to prevent COPD readmissions and mortality after hospital discharge.

Utility of Predictive Systems in Diagnostic Errors (UPSIDE)

Diagnostic errors — delays in recognizing illnesses, problems with interpreting data, and cognitive mistakes that lead physicians to make incorrect clinical decisions — are a major quality of care challenge, one that leads to serious patient harms.


Many factors contribute to diagnostic errors, but key among them are foundational issues in healthcare: complex and fragmented care systems, the limited time available to providers trying to ascertain a firm diagnosis, and the work systems and cultures that support or impede improvements in diagnostic performance.

Inter-hospital Transfers Study

Inter-hospital transfer (IHT, the transfer of patients from one acute care hospital to another) is common among hospitalized medical patients. Despite this, there is a dearth of guidelines or data to help direct best practices regarding which patients most benefit from transfer, or conversely, which patients may be exposed to the risks of discontinuity of care without clear benefit from care received following transfer.

HOMERuN Completed Projects

HOMERuN Pilot Projects